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AMRA-BREAST-01:
A Randomised, Multicentre, Double-Blind, Phase II Clinical Trial Evaluating the Safety and Efficacy of Oral Selective Estrogen Receptor Degrader (SERD) in Metastatic Breast Cancer Patients with ER+ and HER2- Status, Who Have Not Received Prior Systemic Treatment for Advanced Disease
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YND-H-01 in Hematologic Malignancies
This is a Phase 1 dose-escalation study of a potent and highly selective cyclin-dependent kinase (CDK) 9 inhibitor, in participants with select relapsed or refractory (R/R) hematologic malignancies. The purpose of this study is to evaluate the safety, tolerability, recommended phase 2 dose (PR2D), and preliminary efficacy of specific CDK9 Inh.
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